85-4741-59　Ppib, Recombinant, Mouse, aa34-216, His-Tag (Peptidyl-Prolyl Cis-Trans Isomerase B, Cphn-2, Cphn2, CyP-20b) 100ug　377933

特徴

• Ppib, also known as peptidyl-prolyl cis-trans isomerase B, is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A -mediated immunosuppression.
• Source:Recombinant protein corresponding to aa24-188 from mouse Ppib, fused to His-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~22.7kD (207aa), confirmed by MALDI-TOF
• Endotoxin:<1EU/1ug (determined by LAL method)
• Biological Activity:Specific activity is >1000nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA/minute at 37°C in Tris-HCl pH 8.0 using chymotrypsin.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSMNDKKKG PKVTVKVYFD LQIGDESVGR VVFGLFGKTV PKTVDNFVAL ATGEKGFGYK NSKFHRVIKD FMIQGGDFTR GDGTGGKSIY GERFPDENFK LKHYGPGWVS MANAGKDTNG SQFFITTVKT SWLDGKHVVF GKVLEGMDVV RKVESTKTDS RDKPLKDVII VDSGKIEVEK PFAIAKE
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.