85-4741-57　PLAT, Recombinant, Human, aa36-310, His-Tag (Tissue-type Plasminogen Activator Isoform 1, T-PA, TPA) 10ug　377929

特徴

• PLAT, also known as tissue-type plasminogen activator isoform 1, is a protein involved in the breakdown of blood clots. This protein is secreted as a single chain polypeptide precursor which is cleaved in turn by plasmin. Also, active PLAT converts plasminogen to plasmin, a fibrinolytic protease, by hydrolyzing an Arg-Val peptide bond in plasminogen.
• Source:Recombinant protein corresponding to aa36-310 from human PLAT, fused to His-Tag at C-terminal, expressed in insect cell.
• Molecular Weight:~32kD (284aa), 28-40kD (SDS-PAGE under reducing conditions.)
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:ADPSYQVICR DEKTQMIYQQ HQSWLRPVLR SNRVEYCWCN SGRAQCHSVP VKSCSEPRCF NGGTCQQALY FSDFVCQCPE GFAGKCCEID TRATCYEDQG ISYRGTWSTA ESGAECTNWN SSALAQKPYS GRRPDAIRLG LGNHNYCRNP DRDSKPWCYV FKAGKYSSEF CSTPACSEGN SDCYFGNGSA YRGTHSLTES GASCLPWNSM ILIGKVYTAQ NPSAQALGLG KHNYCRNPDG DAKPWCHVLK NRRLTWEYCD VPSCSTCGLR QYSQPQFRHH HHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.