85-4741-27　Mfge8, Recombinant, Mouse, aa23-426, His-Tag (Milk Fat Globule-EGF Factor 8 Protein, Lactadherin, MFG-E8, Mfgm, MP47, P47, SED1) 10ug　377890

特徴

• Mfge8, also known as Milk fat globule-EGF factor 8 protein, is pleiotropic secreted glycoprotein that promotes mammary gland morphogenesis, angiogenesis, and tumor progression. It also plays an important role in tissue homeostasis and the prevention of inflammation. It functions as a bridge between phosphatidylserine on apoptotic cells and Integrin alpha V beta 3 on phagocytes, leading to the clearance of apoptotic debris.
• Source:Recombinant protein corresponding to aa23-426 from mouse Mfge8 protein, fused to His-Tag at C-terminal, expressed in insect cell.
• Molecular Weight:~46.0kD (413aa), 40-57kD (SDS-PAGE under reducing conditions.)
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:ADLASGDFCD SSLCLNGGTC LTGQDNDIYC LCPEGFTGLV CNETERGPCS PNPCYNDAKC LVTLDTQRGD IFTEYICQCP VGYSGIHCET GCSTQLGMEG GAIADSQISA SSVYMGFMGL QRWGPELARL YRTGIVNAWT ASNYDSKPWI QVNLLRKMRV SGVMTQGASR AGRAEYLKTF KVAYSLDGRK FEFIQDESGG DKEFLGNLDN NSLKVNMFNP TLEAQYIKLY PVSCHRGCTL RFELLGCELH GCSEPLGLKN NTIPDSQMSA SSSYKTWNLR AFGWYPHLGR LDNQGKINAW TAQSNSAKEW LQVDLGTQRQ VTGIITQGAR DFGHIQYVAS YKVAHSDDGV QWTVYEEQGS SKVFQGNLDN NSHKKNIFEK PFMARYVRVL PVSWHNRITL RLELLGCHHH HHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.