Klk8, as known as kallikrein-8, is a member of the tissue kallikrein family. This protein is capable of degrading a number of proteins such as casein, fibrinogen, fibronectin and collagen type IV. Also, it cleaves L1CAM in response to increased neural activity and induces neurite outgrowth and fasciculation of cultured hippocampal neurons. It plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer- collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity.
Source:Recombinant protein corresponding to aa29-260 from mouse Klk8, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~26.5kD (240aa) 28-40kD (SDS-PAGE under reducing conditions.)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Source Antigen：Recombinant, Baculovirus
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
