KLK5, also known as kallikrein-5, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. It is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14.
Source:Recombinant protein corresponding to aa67-293 from human KLK5, fused to His-Tag at C-terminal, expressed in insect cell.
Recombinant protein corresponding to aa67-293 from human KLK5, fused to His-Tag at C-terminal, expressed in E. Coli
Accession: NP_001070960
Molecular Weight:~26.2kD (236aa), 28-40kD (SDS-PAGE under reducing conditions.)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Source Antigen：Recombinant, E. Coli.
Grade：Highly Purified
Purity：~95% (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
