KLK15, also known as kallikrein-15 isoform 4, is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. Also, growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In prostate cancer, it has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer.
Source:Recombinant protein corresponding to aa24-188 from human KLK15, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~27.4kD (249aa), 28-40kD (SDS-PAGE under reducing conditions.)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：10ug
Source Antigen：Recombinant, Baculovirus
Grade：Purified
Purity：~80% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
