85-4741-01　IL5, Recombinant, Human, aa20-134, His-Tag (Interleukin-5, IL-5, EDF, TRF) 10ug　377863

特徴

• IL5, also known as interleukin-5, is a member of the hematopoietin receptor superfamily and is comprised of a cytokine-specific alpha chain and the common beta chain that is shared among these cytokines for signaling. It related hematopoietic cytokines that are important for allergic inflammation. It is a lineage-specific cytokine for eosinophilpoiesis and plays an important part in diseases associated with increased eosinophils, such as asthma.
• Source:Recombinant protein corresponding to aa20-134 from human IL5, fused to His-Tag at C-terminal, expressed in insect cell.
• Molecular Weight:~14.2kD (124aa), 13.5-18kD (SDS-PAGE under reducing conditions)
• Endotoxin:<1EU/1ug (determined by LAL method)
• Biological Activity:Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 for this effects is ≤1.5ng/ml.
• AA Sequence:ADPIPTEIPT SALVKETLAL LSTHRTLLIA NETLRIPVPV HKNHQLCTEE IFQGIGTLES QTVQGGTVER LFKNLSLIKK YIDGQKKKCG EERRRVNQFL DYLQEFLGVM NTEWIIESHH HHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.