85-4740-13　Creg1, Recombinant, Mouse, aa32-220, His-Tag (Cellular Repressor of E1A-stimulated Genes 1, Creg) 500ug　377771

特徴

• Creg1, also known as Cellular repressor of E1A-stimulated genes1, was antagonizes transcriptional activation and cellular transformation by E1A. This protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Creg1 increases EC filopodia formation and vascular assembly via ILK-Cdc42 activation and promotes neovascularization, which might be a therapeutic target for ischemic injury.
• Source:Recombinant protein corresponding to aa32-220 from mouse Creg1 protein, fused to His-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~24kD (213aa)
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSMRGGRDH GDWDVDRRLP PLPPREDGPR VARFVTHVSD WGSLATISTI KEVRGWPFAD IISISDGPPG EGTGEPYMYL SPLQQAVSDL QENPEATLTM SLAQTVYCRN HGFDPQSPLC VHIMMSGTVT KVNKTEEDYA RDSLFVRHPE MKHWPSSHNW FFAKLKISRI WVLDYFGGPK VVTPEEYFNV TLQ
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.