CD84, also known as slam family member 5 isoform 1, is a self-binding receptor from the CD150 family that is broadly expressed in hematopoietic cells. It is highly expressed in mast cells and that it contributes to the regulation of FceRI signaling in SAP- and EAT-2-independent and Fes- and Src homology region 2 domain- containing phosphatase-1-dependent mechanisms. It belongs to the signaling lymphocyte activating molecule family of immunoreceptors, and has an unknown function in CLL cells. Its expression is significantly elevated from the early stages of the disease, and is regulated by macrophage migration inhibitory factor and its receptor, CD74.
Source:Recombinant protein corresponding to aa22-225 from human CD84, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~23.8kD (213aa), 28-40kD (SDS-PAGE under reducing conditions.)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Source Antigen：Recombinant, Baculovirus
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
