85-4739-92　CD80, Recombinant, Human, aa35-242, His-Tag (T-lymphocyte Activation Antigen CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7) 20ug　377748

特徴

• CD80, also known as T-lymphocyte activation antigen CD80, is a member of cell surface immunoglobulin superfamily. This protein can bind to either human or mouse CD28 and CTLA-4. It is expressed on activated B cells, activated T cells, and macrophages. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. Therefore, it is considered a promising therapeutic target for autoimmune diseases and various carcinomas.
• Source:Recombinant protein corresponding to aa35-242 from human CD80, fused to His-tag at C-terminal, expressed in insect cell.
• Molecular Weight:~24.9kD (216aa) 28-40kD (SDS-PAGE under reducing conditions)
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:VIHVTKEVKE VATLSCGHNV SVEELAQTRI YWQKEKKMVL TMMSGDMNIW PEYKNRTIFD ITNNLSIVIL ALRPSDEGTY ECVVLKYEKD AFKREHLAEV TLSVKADFPT PSISDFEIPT SNIRRIICST SGGFPEPHLS WLENGEELNA INTTVSQDPE TELYAVSSKL DFNMTTNHSF MCLIKYGHLR VNQTFNWNTT KQEHFPDNLE HHHHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.