Histone H4 (1-23) monomethylated at Arg3 followed by a biotinylated Lys conjugated to a C-terminal GG linker. Methylation of Arg3 is catalyzed by PRMT1 and functions to promote p300 acetylation of histone H4.
Molecular Weight:~2843.4
AA Sequence:G-R(Me1)-GKGGKGLGKGGAKRHRKVLRGG-K(Biotin)
Applications:Suitable for use as a substrate for arginine methyltransferases and for screening small molecular inhibitors of Histone 4 (R3) methyltransferases for drug discovery. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:40nmole
Source Antigen:Synthetic peptide
Grade:Highly Purified
Purity:~95% (HPLC)
Form:Supplied as a 200uM solution in 200ul of H2O. Labeled with Biotin.