85-4734-97　UL111A, Recombinant, Human, aa26-176 (Cytomegalovirus Viral interleukin-10 Homolog) 20ug　375768

特徴

• Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells.
• Source:Recombinant protein corresponding to aa26-176 from human UL111A, expressed in E. coli.
• Molecular Weight:~17.5kD
• AA Sequence:ATTTTIKNTKPQCRPEDYATRLQDLRVTFHRVKPTLQREDDYSVWLDGTVVKGCWGCSVMDWLLRRYLEIVFPAGDHVYPGLKTELHSMRSTLESIYkDaMRQCPLLGCGDKSVISRLSQEAERKSDNGTRKGLSELDTLFSRLEEYLHSRK
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：20ug
• Source Antigen：Recombinant, E. coli
• Grade：Purified
• Purity：~90% (SDS-PAGE)
• Form：Supplied as a liquid in Tris, 50% glycerol.
• Molecular Weight Non Ab：17.5
• Swiss Prot Number：F5HC71 
• EU Commodity Code：30021019
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