85-4725-55　Sigirr, Recombinant, Mouse, aa1-117, His-SUMO-Tag (Single Ig IL-1-related Receptor) 100ug　375296

特徴

• Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its Extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).
• Source:Recombinant protein corresponding to aa1-117 from mouse Sigirr, fused to His-SUMO-Tag at N-terminal expressed in E. coli.
• Molecular Weight:~28.7kD
• AA Sequence:MAGVCDMAPNFLSPSEDQALGLALGREVALNCTAWVFSRPQCPQPSVQWLKDGLALGNGSHFSLHEDFWVSANFSEIVSSVLVLNLTNAEDYGTFTCSVWNVSSHSFTLWRAGPAGH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：100ug
• Source Antigen：Recombinant, E. coli
• Grade：Purified
• Purity：≥90% (SDS-PAGE)
• Form：Supplied as a liquid in Tris-HCl, pH 8.0, 1mM EDTA, 50% glycerol.
• Molecular Weight Non Ab：28.7
• Swiss Prot Number：Q9JLZ8 
• EU Commodity Code：30021019
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