85-4707-67　NEDD8, Recombinant, Human, aa1-81, GST-Tag (NEDD8) 100ug　374397

特徴

• Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
• Source:Recombinant protein corresponding to aa1-81 from human NEDD8, fused to GST-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~35.6kD
• Amino Acid Sequence:MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGG
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：100ug
• Source Antigen：Recombinant, E. coli
• Grade：Purified
• Purity：≥90% (SDS-PAGE)
• Form：Supplied as a liquid in Tris, 50% glycerol.
• Molecular Weight Non Ab：35.6
• Swiss Prot Number：Q15843
• EU Commodity Code：30021019
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