TPST2, also known as protein-tyrosine sulfotransferase 2, is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. This protein is a type II integral membrane protein found in the Golgi body. Compared to TPST1, TPST2 has similar tissue distribution and overlapping substrate specificity. In contrast to TPST1-/- males with normal fertility in mice, TPST2-/- males are infertile due to severe defects in sperm motility.
Source:Recombinant protein corresponding to aa26-377 from human TPST2, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~40.4kD (361aa) 40-57KD (SDS-PAGE under reducing conditions.)
Endotoxin:~1EU/1ug (LAL)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:50ug
Source Antigen:Recombinant, human from insect cell line
Grade:Highly Purified
Purity:~95% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.