TNFSF8, also known as tumor necrosis factor ligand superfamily member 8, is a type II membrane protein belonging to the TNF superfamily. It is expressed on the cell surface of activated T cells, B cells, and monocytes. CD30/TNFRSF8 ligation by TNFSF8 mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis.
Source:Recombinant protein corresponding to aa63-234 from human TNFSF8, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~20.7kD (181aa) 18-40KD (SDS-PAGE under reducing conditions.)
AA Sequence:ADPQRTDSIP NSPDNVPLKG GNCSEDLLCI LKRAPFKKSW AYLQVAKHLN KTKLSWNKDG ILHGVRYQDG NLVIQFPGLY FIICQLQFLV QCPNNSVDLK LELLINKHIK KQALVTVCES GMQTKHVYQN LSQFLLDYLQ VNTTISVNVD TFQYIDTSTF PLENVLSIFL YSNSDHHHHH H
Endotoxin:~1EU/1ug (LAL)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:20ug
Source Antigen:Recombinant, human from insect cell line
Grade:Purified
Purity:~85% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.