PLAUR, as known as urokinase plasminogen activator surface receptor isoform 1, is one of two activators that converts the extracellular zymogen plasminogen to plasmin, a serine protease that is involved in a variety of normal and pathological processes that require cell migration and/or tissue destruction. This protein is synthesized and released from cells as a single-chain proenzyme with limited enzymatic activity and is converted to an active two-chain disulfide-linked active enzyme by plasmin and other specific proteinases.
Source:Recombinant protein corresponding to aa23-305 from human PLAUR, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~32.5kD (291aa) 40-57kD (SDS-PAGE under reducing conditions)
Endotoxin:~1EU/1ug (LAL)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, human from insect cell line
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
