LUM, also known as lumican, is a member of the class II small leucine-rich proteoglycan family. It is a major component of the cornea, dermal, and muscle connective tissues. It regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and is also present in the connective tissues of other organs and embryonic corneal stroma as a glycoprotein. It may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Source:Recombinant protein corresponding to aa19-338 from human LUM, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~37.7kD (329aa) 40-57kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:50ug
Source Antigen:Recombinant, human from insect cell line
Grade:Highly Purified
Purity:~95% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.