85-4642-22　IL4, Recombinant, Mouse, aa25-153 (Interleukin 4 Isoform1) 50ug　369081

特徴

• IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1.
• Source:Recombinant protein corresponding to aa25-153 from mouse IL4, expressed in E. coli.
• Molecular Weight:~15kD (130aa)
• AA Sequence:MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
• Endotoxin:~1EU/1ug (LAL)
• Biological activity:Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is ≤0.6ng/ml.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.