CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a surface molecule which has been attributed the function of a signaling channel leading to cellular activation and proliferation, an ectoenzyme with multiple function as well as an inducer of Ca2+ mobilization from cytoplasmic stores. It also functions as a plasma membrane signaling receptor in leukocytes. On B cells, It acts as a coreceptor and modulates B cell receptor (BCR) signals.
Source:Recombinant protein corresponding to aa43-300 from human CD38, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~31.2kD (269aa) 28-40KD (SDS-PAGE under reducing conditions.)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, human from insect cell line
Grade：Purified
Purity：≥90% (SDS-PAGE). Endotoxin: ~1EU/1ug (LAL)
Form：Supplied as a liquid in 50mM MES, pH 5.0, 100mM sodium chloride, 10% glycerol.
