CD27, as known as CD27 antigen, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycosylation on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD 70 on lymphocytes and dendritic cells. This protein plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
Source:Recombinant protein corresponding to aa21-191 from human CD27, fused to hlgG-His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~46.4kD (413aa) 28-57kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:20ug
Source Antigen:Recombinant, human from insect cell line
Grade:Purified
Purity:~85% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.