Chemical Name:4-[2-[[2-(1-benzothiophen-3-yl)-9-propan-2-ylpurin-6-yl]amino]ethyl]phenol
Molecular Formula:C24H23N5OS
Molecular Weight:429.5
Purity:≥98%
Applications:FA
Appearance:Crystalline solid
Description:StemRegenin 1 (SR1) is a selective reversible antagonist of the aryl hydrocarbon receptor with a value of 50% inhibition concentration IC50 of 127 nM in CD34+ cells. It is reported to promote the self-renewal of human hematopoietic stem cells in culture by sustaining the cellular expression of CD34. StemRegenin 1 also stimulates the proliferation and differentiation of CD34+ hematopoietic progenitor cells into dendritic cells.
Solubility:Soluble in organic solvents such as DMSO. DMSO up to 25mM.
Storage:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
