Chemical Name:N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Molecular Formula:C27H25F3N8O2
Molecular Weight:550.5
Purity:≥98%
Applications:FA
Appearance:Crystalline solid
Description:Pluripotin is an inhibitor of both RasGAP and ERK1. The inhibition of RasGAP is used to promote self-renewal and the inhibition of ERK1 blocks cell differentiation. Pluripotin can be conbined with leukemia inhibitory factor (LIF) to promote the derivation of embryonic cell lines from refractory strains.
Storage:Soluble in organic solvents such as DMF and DMSO. DMSO up to 45mM.
