Chemical Name:2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N- (6-methyl-2-benzothiazolyl)-acetamide
Molecular Formula:C22 H17 FN 4O2S3
Molecular Weight:484.6
Purity:≥98%
Applications:FA
Appearance: Crystalline solid
Description:IWP-3 is a Wnt pathway inhibitor by inactivating the Porcupine O-acyltransferase which palmitoylates Wnt proteins. It is reported to inhibit embryonic stem cell self-renewal and promote cardiomyocyte differentiation from human stem cells.
Storage:Soluble in organic solvents such as DMF and DMSO. DMF up to 4mM.