Hepatitis C Virus is a single-stranded, positive RNA flavivirus that causes severe liver disease. Initial and early chronic infection is usually mild or asymptomatic, but often progresses to liver disease, cirrhosis, liver failure and liver cancer. Transmission is primarily by blood-to-blood contact associated with intravenous drug use or transfusions, affecting an estimated 170 million people annually.
Nonstructural protein 3 (NS3), is a nonstructural viral protein derived from the HCV polyprotein. It is an essential viral protein with serine protease and RNA helicase activity. It is expressed early in the viral replication cycle and as such is a good candidate for early detection of infection.
Source:Recombinant protein corresponding to HCV NS3 expressed in E. coli.
Molecular Weight:~48.7kD
Activity:Binds HCV positive serum antibodies
Applications:Suitable for use in ELISA, Western Blot and Lateral Flow. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：1mg
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：≥95% (SDS-PAGE)
Form：Supplied as a lyophilized powder in 20mM carbonate, pH 9.6. No preservative added.
