85-4621-19　［取扱停止］CCL1, Recombinant, Human (C-C Motif Chemokine 1, I-309, P500, SCYA1, SISe, TCA3) 10ug　359931

特徴

• This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
• Source:Recombinant protein corresponding to human I-309/CCL1, a single, non-glycosylated polypeptide chain containing 74aa, expressed in E. coli.
• Molecular Weight:~8.5kD (74aa)
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Biological ActivityFully biologically active when compared to standard. Determined by its ability to chemoattract total human T cell population using a concentration range of 10-100ng/ml, corresponding to a specific activity of ＞1x10e4IU/mg.
• Endotoxin:<1EU/mg (LAL)
• AA Sequence:SKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK
• Storage and Stability:Lyophilized powder may be stored at -20°C. Reconstitute with sterile dH2O, 0.1% BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.