85-4492-71　SAP14, Recombinant, Human, aa1-125, His-Tag (SF3B14, SAP14, Splicing factor 3B 14kD Subunit, CGI-110, HSPC175, Ht006, P14, SF3B14a) 50ug　351487

特徴

• SF3B14, also known as SAP14, is a 125aa nuclear protein that is a component of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. Required for the splicing of pre-mRNA, SF3B14 enters the spliceosome and associates with the pre-mRNA branch site facilitating the interaction of snRNP with the branch sites of U2 and U12 of the 17S U2 and the 18S U11/U12 snRNP complex.
• Source:Recombinant protein corresponding to aa1-125 from human SF3B14, fused to His-tag at N-terminal expressed in E. coli.
• Molecular Weight:~16.7kD (145aa)
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV GNTPETRGTA YVVYEDIFDA KNACDHLSGF NVCNRYLVVL YYNANRAFQK MDTKKKEEQL KLLKEKYGIN TDPPK
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.