85-4492-23　PTP4A2, Recombinant, Human, aa1-167, His-Tag (Protein tyrosine phosphatase type IVA 2 Isoform 1, HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, Ptp-IV1a, Ptp-IV1b, PTP4A, PTPCAAX2) 50ug　351462

特徴

• Protein tyrosine phosphatase type IVA 2 isoform 1, also known as PTP4A2, belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that play regulatory roles in a variety of cellular processes. This protein was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis.
• Source:Recombinant protein corresponding to aa1-167 from human PTP4A2, fused to His-tag at N-terminal expressed in E. coli.
• Molecular Weight:~23.2kD (203aa)
• AA Sequence:MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNRP APVEISYENM RFLITHNPTN ATLNKFTEEL KKYGVTTLVR VCDATYDKAP VEKEGIHVLD WPFDDGAPPP NQIVDDWLNL LKTKFREEPG CCVAVHCVAG LGRAPVLVAL ALIECGMKYE DAVQFIRQKR RGAFNSKQLL YLEKYRPKMR LRFRDTNGHC CVQ
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.