85-4491-06　NME3, Recombinant, Human, aa22-169, His-Tag(Nucleoside diphosphate Kinase 3, c371H6.2, DR-nm23, KIAA0516, NDPK-C, NDPKC, NM23-H3, NM23H3) 20ug　351395

特徴

• NME3, also known as, a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. It is important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis. It is preferentially expressed during early stages of myeloid differentiation of highly purified CD34+ cells.
• Source:Recombinant protein corresponding to aa22-169 from human NME3, fused to His-tag at N-terminal expressed in E. coli.
• Molecular Weight:~19.1kD (169aa)
• Specific Activity:>150units/mg, and is defined as the amount of enzyme that convert 1umole each of ATP and TDP to ADP and TTP/minute at pH 7.5 at 25°C in a couple system with PK/LDH.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MERTFLAVKP DGVQRRLVGE IVRRFERKGF KLVALKLVQA SEELLREHYA ELRERPFYGR LVKYMASGPV VAMVWQGLDV VRTSRALIGA TNPADAPPGT IRGDFCIEVG KNLIHGSDSV ESARREIALW FRADELLCWE DSAGHWLYE
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.