85-4488-85　Gstp1, Recombinant, Mouse, aa1-210, His-Tag (Glutathione S-Transferase P1, GstpiB) 500ug　351272

特徴

• Gstp1 also known as Glutathione S-transferase P 1. Gstp1 is a superfamily of ubiquitously expressed cytosolic, mitochondrial and membrane-associated enzymes involved in a range of detoxification processes. Also Increased Gstp1 levels were consistently associated with reduced Cdk5 activity. Gstp1 directly inhibits Cdk5 by dislodging p25/p35, and indirectly by eliminating oxidative stress.
• Source:Recombinant protein corresponding to aa1-210 from mouse Gstp1, fused to His-tag at N-terminal expressed in E. coli.
• Molecular Weight:~26kD(233aa)
• Specific Activity:>40 units/mg, and is defined as the amount of enzyme that conjugate 1umole of 1-chloro-2,4-dinitrobenzene (CDNB) with reduced glutathione/minute at pH 6.5 at 25°C.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSMPPYTIV YFPVRGRCEA MRMLLADQGQ SWKEEVVTID TWMQGLLKPT CLYGQLPKFE DGDLTLYQSN AILRHLGRSL GLYGKNQREA AQMDMVNDGV EDLRGKYVTL IYTNYENGKN DYVKALPGHL KPFETLLSQN QGGKAFIVGD QISFADYNLL DLLLIHQVLA PGCLDNFPLL SAYVARLSAR PKIKAFLSSP EHVNRPINGN GKQ
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.