85-4487-73　Ep-CAM, Recombinant, Human, aa24-265, His-Tag (TACSTD1, Epithelial Cell Adhesion Molecule, Tumor-associated calcium signal transducer 1, CD326, CO17-1A, EGP, EGP40, GA733-2, hEGP-2, KSA, M4S1, MIC18, MK-1, TROP1) 50ug　351209

特徴

• TACSTD1, also known as tumor-associated calcium signal transducer 1, is a membrane glycoprotein expressed on adenomatous and simple epithelia, where it is involved in homophilic adhesion at the basolateral membrane. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation.
• Source:Recombinant protein corresponding to aa24-265 from human TACSTD1, fused to His-tag at C-terminal expressed in insect cell.
• Molecular Weight:~28.2kD (248aa)
• AA Sequence:QEECVCENYK LAVNCFVNNN RQCQCTSVGA QNTVICSKLA AKCLVMKAEM NGSKLGRRAK PEGALQNNDG LYDPDCDESG LFKAKQCNGT STCWCVNTAG VRRTDKDTEI TCSERVRTYW IIIELKHKAR EKPYDSKSLR TALQKEITTR YQLDPKFITS ILYENNVITI DLVQNSSQKT QNDVDIADVA YYFEKDVKGE SLFHSKKMDL TVNGEQLDLD PGQTLIYYVD EKAPEFSMQG LKHHHHHH
• Endotoxin: ~1EU/1ug (LAL)
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.