85-4486-73　CFD, Recombinant, Human, aa21-253, His-Tag (Complement factor D preproprotein) 50ug　351153

特徴

• CFD, also known as Complement factor D preproprotein, is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. There are two antiparallel beta-barrel domains with each barrel containing six beta-strands with the same typology in all enzymes. The major difference in backbone structure between Factor D and the other serine proteases of the chymotrpsin family is in the surface loops connecting the secondary structural elements. Factor D displays different conformations of major catalytic and substrate-binding residues typically found in the chrotrypsin family.
• Source:Recombinant protein corresponding to aa21-253 from human CFD fused to His-tag at C-terminal expressed in insect cell.
• Molecular Weight:~26.01kD (241aa)
• AA Sequence:PPRGRILGGR EAEAHARPYM ASVQLNGAHL CGGVLVAEQW VLSAAHCLED AADGKVQVLL GAHSLSQPEP SKRLYDVLRA VPHPDSQPDT IDHDLLLLQL SEKATLGPAV RPLPWQRVDR DVAPGTLCDV AGWGIVNHAG RRPDSLQHVL LPVLDRATCN RRTHHDGAIT ERLMCAESNR RDSCKGDSGG PLVCGGVLEG VVTSGSRVCG NRKKPGIYTR VASYAAWIDS VLAVEHHHHH H
• Endotoxin: ~1EU/1ug (LAL)
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.