85-4486-22　Cathepsin E, Recombinant, Mouse, aa21-397, His-Tag (CTSE) 50ug　351125

特徴

• CTSE, also known as cathepsin E, belongs to an intracellular aspartic protease of the pepsin family. It plays an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. It is efficient in cleaving the Swedish mutant of amyloid precursor protein (APP) at the B site but show almost on reactivity with the wild-type APP.
• Source:Recombinant protein corresponding to aa21-397 from mouse CTSE, fused to His-tag at C-terminal expressed in Insect cell.
• Molecular Weight:~41.8kD (385aa)
• AA Sequence:ALHRVPLRRH QSLRKKLRAQ GQLSEFWRSH NLDMTRLSES CNVYSSVNEP LINYLDMEYF GTISIGTPPQ NFTVIFDTGS SNLWVPSVYC TSPACKAHPV FHPSQSDTYT EVGNHFSIQY GTGSLTGIIG ADQVSVEGLT VDGQQFGESV KEPGQTFVNA EFDGILGLGY PSLAAGGVTP VFDNMMAQNL VALPMFSVYL SSDPQGGSGS ELTFGGYDPS HFSGSLNWIP VTKQAYWQIA LDGIQVGDTV MFCSEGCQAI VDTGTSLITG PPDKIKQLQE AIGATPIDGE YAVDCATLDT MPNVTFLINE VSYTLNPTDY ILPDLVEGMQ FCGSGFQGLD IPPPAGPLWI LGDVFIRQFY SVFDRGNNQV GLAPAVPLEH HHHHH
• Endotoxin: ~1EU/1ug (LAL)
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.