85-4484-35　UTP23, Recombinant, Human, aa1-249, His-Tag (RNA-processing protein uTP23 homolog) 500ug　350383

特徴

• RNA-processing protein uTP23 homolog, also known as uTP23, is a small subunit (SSu) processome component. The SSu processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. uTP23 is required for the first three cleavage steps in 18S rRNA maturation. In addition, single-point mutations in the conserved putative active site of utp24 but not utp23 abrogate its function in ribosome biogenesis.
• Source:Recombinant protein corresponding to aa1-249 of human UTP23, fused to His-tag at N-terminal expressed in E. coli.
• Molecular Weight:~30.8kD
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSMKITRQK HAKKHLGFFR NNFGVREPYQ ILLDGTFCQA ALRGRIQLRE QLPRYLMGET QLCTTRCVLK ELETLGKDLY GAKLIAQKCQ VRNCPHFKNA VSGSECLLSM VEEGNPHHYF VATQDQNLSV KVKKKPGVPL MFIIQNTMVL DKPSPKTIAF VKAVESGQLV SVHEKESIKH LKEEQGLVKN TEQSRRKKRK KISGPNPLSC LKKKKKAPDT QSSASEKKRK RKRIRNRSNP KVLSEKQNAE GE
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.