85-4457-45　［取扱停止］Tumor Necrosis Factor Receptor Superfamily Member 17, active (TNFRSF17), Recombinant, Human 100ug　348260

特徴

• Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40ng/ml, corresponding to a specific activity of ＞ 2.5x10e4 IU/mg in the presence of 100ng/ml human APRIL.
• Sequence:AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
• Molecular Weight:5.4kD
• PubMed ID:1396583; 8165126; 11528522; 17825416; 10493829; 15616553; 10903733; 10801128; 10973284; 10908663; 12721620; 15542592
• Gene Name:TNFRSF17,BCM,BCMA
• Swiss Prot:Q02223
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.