85-4455-97　［取扱停止］Proepiregulin, cleaved to Epiregulin, active (EREG), Recombinant, Human 100ug　348211

特徴

• Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. {ECO:0000269|PubMed:9419975}.
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 2ng/ml, corresponding to a specific activity of ＞ 5.0x10e5 IU/mg.
• Sequence:VAQVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL
• Molecular Weight:5.6kD
• PubMed ID:9337852; 14702039; 15489334; 9419975; 14572630; 16959974
• Gene Name:EREG
• Swiss Prot:O14944
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.