85-4455-91　Probetacellulin, cleaved to Betacellulin, active (BTC), Recombinant, Human 5ug　348210

特徴

• Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}.
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.05ng/ml, corresponding to a specific activity of ＞ 2.0x10e7 IU/mg.
• Sequence:DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
• Molecular Weight:9.0kD
• PubMed ID:8439318; 15489334; 8144591; 8919026; 8570211; 10867024; 12074582
• Gene Name:BTC
• Swiss Prot:P35070
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.