85-4452-97　Interleukin-20, active (IL20), Recombinant, Human 10ug　348117

特徴

• Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. {ECO:0000269|PubMed:16511554}.
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 0.5ng/ml, corresponding to a specific activity of ＞2×10e6 IU/mg.
• Sequence:MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
• Molecular Weight:17.6kD
• PubMed ID:11163236; 16511554; 12975309; 16710414; 15489334; 15340161; 16908179; 16709143; 22802649
• Gene Name:IL20, ZCYTO10, UNQ852/PRO1801
• Swiss Prot:Q9NYY1
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.