85-4452-76　［取扱停止］Interleukin-17A, active (IL17A), Recombinant, Human 25ug　348111

特徴

• Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 7.5ng/ml, corresponding to a specific activity of ＞ 1.3x10e5 IU/mg.
• Sequence:GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA
• Molecular Weight:31.0kD
• PubMed ID:8676080; 7499828; 14574404; 15489334; 15340161; 19835883
• Gene Name:IL17A,CTLA8,IL17
• Swiss Prot:Q16552
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.