85-4451-05　［取扱停止］Glial cell line-derived neurotrophic factor, active (GDNF), Recombinant, Human 250ug　348058

特徴

• Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. {ECO:0000269|PubMed:8493557}.
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.1ng/ml, corresponding to a specific activity of ＞ 5.0x10e7 IU/mg.
• Sequence:SPDKQMAVLP RRERNRQAAA ANPENSRGKG RRGQRGKNRG CVLTAIHLNV TDLGLGYETK EELIFRYCSG SCDAAETTYD KILKNLSRNR RLVSDKVGQA CCRPIAFDDD LSFLDDNLVY HILRKHSAKR CGCI
• Molecular Weight:30.1kD
• PubMed ID:8493557; 7867768; 15372022; 15489334; 10e366742; 9811930; 8988018; 22081608; 9359036; 19478429; 8968758; 8896568; 8896569; 9497256; 10917288
• Gene Name:GDNF
• Swiss Prot:P39905
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.