85-4450-97　Galectin-1, active (LGALS1), Recombinant, Human 10ug　348056

特徴

• May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. {ECO:0000269|PubMed:14617626, ECO:0000269|PubMed:18796645, ECO:0000269|PubMed:19497882}.
• Biological Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10ng/ml.
• Sequence:ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD
• Molecular Weight:14.6kD
• PubMed ID:2719964; 2910856; 2719646; 18824694; 1988031; 12761501; 15461802; 14702039; 10591208; 15489334; 3065332; 12665801; 3611046; 1386213; 2383549; 7501023; 10e369126; 10764829; 11146440; 14617626; 19497882; 19608861; 21269460; 22905912; 22223895; 22814378; 23131994; 24275569; 260910e39; 15476813; 18796645; 19128029
• Gene Name:LGALS1
• Swiss Prot:P09382
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.