85-4448-76　［取扱停止］C-X-C motif chemokine 11, active (CXCL11), Recombinant, Human 100ug　347996

特徴

• Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
• Biological Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10ng/ml.
• Sequence:FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
• Molecular Weight:8.3kD
• PubMed ID:8798467; 9370294; 9625760; 10233762; 10e386863; 10e395932; 15489334; 9730616; 18645041; 15273303
• Gene Name:CXCL11,ITAC,SCYB11,SCYB9B
• Swiss Prot:O14625
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.