The HMGI family of proteins are architectural transcription factors and consists of three members, HMGIC, HMGI and HMGI(Y). Recent research results implicate HMGIC as playing a central role in obesity. Mice with a partial or complete deficiency in HMGIC expression resisted diet and leptin induced obesity.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
