TSST-1 is a pyrogenic toxin superantigen secreted by Staphylococcus aureus. TSST-1 is a powerful activator of T-lymphocytes resulting in substantial cytokine release that can cause severe pathological consequences.
rTSST-1 can be utilized as a control in ELISA and Western blot assays, as a potent mitogen, or as an activator of cytokines in Peripheral Blood Mononuclear Cells (PBMC).
Recombinant TSST-1 expressed in E. coli and purified to >90% using chromatographic methods.
Applications:Suitable for use in ELISA, Western Blot and PBMC Stimulation assay. Other applications not tested.
Recommended Dilutions:PBMC Stimulation assay: 0.1ng/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
