85-4423-39　［取扱停止］CD146, Recombinant, Human, aa433-647 (Mucin 18, MUC18 Glycoprotein, Melanoma Associated Antigen A32, S-Endo 1 Endothelial Associated Antigen, Melanoma Adhesion Molecule Mel-CM) 5ug　299334

特徴

• CD146 (aa433-647) belongs to the immunoglobulin supergene family with five immunoglobulin like domains (V-V-C2-C2-C2), a transmembrane region and a 63 residue cytoplasmic tail. The protein is a membrane glycoprotein that functions as a Ca2+ independent cell adhesion molecule involved in heterophilic cell to cell interactions. CD146 has a molecular size of 130kD in its reduced form (118kD unreduced), and N linked glycosylation accounts for fifty percent of the apparent molecular weight. In some cells the molecule carries a sulfate 3 glucuronyl moiety.
• Source:Recombinant protein corresponding to aa433-647 of human CD146, expressed in E. coli.
• Molecular Weight:~47kD (SDS-PAGE)
• Applications:Suitable for use in ELISA, Western Blot and Inhibition Assays. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.