The BRCA1 protein is a tumor suppressor and is directly involved in DNA repair. Mutations in the BRCA1 gene have been implicated in hereditary breast and ovarian cancer.
Source:Recombinant protein corresponding to aa1-1863 of human BRCA1, fused to polyhistidine-tag at N-terminal, expressed in Baculovirus.
Molecular Weight:~205kD
Applications:Suitable for use in in vitro function studies including transcription and DNA repair, for protein-protein interaction assays and cell growth assays. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：2ug
Source Antigen：Recombinant, Baculovirus
Grade：Highly Purified
Purity：~95% (FPLC chromatography)
Form：Supplied as a lyophilized powder. Reconstitute with 20mM Tris-Cl, pH 8.0, 100mM KCl, 1mM DTT, 0.2mM EDTA, 20% glycerol.
