The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008].
Source:Recombinant protein corresponding to aa72-199 from human glucocorticoid-induced TNF-related ligand, fused to His-tag at N-terminal, expressed in HEK293 cells.
Molecular Weight:~17.1kD, this protein runs at a higher MW by SDS-PAGE due to glycosylation
Endotoxin:<1EU/ug
Applications:Suitable for use in studying protein binding and for screening small molecules and antibodies. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Source Antigen:Recombinant, HEK293 cells
Grade:Highly Purified
Purity:Highly Purified (~90%)
Form:Supplied as a liquid in 40mM Tris-HCl, pH 8.0, 110mM sodium chloride, 2.2mM KCl, 20% glycerol.