85-4307-85　Zanamivir Hydrate 100mg　CAS No:551942-41-7　295106

特徴

• Potent and selective inhibitor of influenza A and B sialidases (neuraminidases). This compound is a sialic acid analogue that occupies viral neuraminidase active site, inhibits enzyme’s hydrolytic activity and cleavage of sialic acid residues from host cell surface glycans. It therefore prevents shedding newly produced virions from infected cell surface and reduces infection of surrounding cells.
• Synonyms:Relenza; GG 167; 2,3-Didehydro-2,4-dideoxy-4-guanidine-N-acetyl-acetyl-D-neuraminic acid; 4-Guanidino-2,4-dideoxy-2,3-didehydro-N-acetylneuraminic acid; 5-Acetamino-2,6-anhydro-4-guanidino-3,4,5-trideoxy-D-galcto-non-enoic acid
• Molecular Formula:C12H22N4O8
• Molecular Weight:332.31
• Purity (HPLC):≥98%
• Appearance:White to off-white powder
• Identity (IR):Conforms to structure
• Melting Point:As Reported
• Specific Optical Rotation ([α]20 (c=0.9, H O): D. 2):+33 to +42°
• Storage and Stability:Store at -20ºC. Stable for 6 months after receipt.