85-4062-28　Simvastatin 10g　CAS No:79902-63-9　289145

特徴

• A competitive inhibitor of HMG-CoA reductase. A synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
• Synonyms:2,2-Dimethylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin; Cholestat; Lipex; Novo-Simvastatin; Simvotin; Sinvacor; Statin; Zorced; MK-733, Synvinolin, BRN 4768037; Zocor, Liponorm
• Molecular Formula:C₂₅H₃₈O₅
• Molecular Weight:418.57
• Appearance:White solid
• Purity:≥98%
• Specific Optical Rotation ([α]20 (c=0.5, AcN): D):+285 to +298°
• Loss on Drying:≤0.5%
• Melting Point:127-132 °C (lit.)
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.