85-3988-76　PLX4032 (Vemurafenib) 1g　CAS No:918504-65-1　287416

特徴

• Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600.
• Identity (1H NMR):Conforms to structure
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note:As of September 2011 the current correct CAS number for vemurafenib, also known as PLX4032, is given above. Chemical Abstracts Service recently canceled another CAS number, 1029872-54-5, that had previously been used for vemurafenib under its older name, PLX4032. However, this canceled number remains in wide use and receives the vast majority of hits on Google.

仕様

• Size：1g
• Grade：Highly Purified
• Purity：≥99% (HPLC)
• Form：Supplied as a white to off-white powder
• Molecular Formula：C23H18ClF2N3O3S
• Molecular Weight Non Ab：489.92
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：918504-65-1

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